Cellular Imaging and Electrophysiology Laboratory

Prof. Dr. Hale Saybasili

Research Fields:

• Electrophysiological recordings from brain slice cells and imaging of intracellular ionic movements are accomplished. Also mechanisms of pathological and pharmocological approaches are studied.

• Electrical activity measurements and potential for modelling neurodegenerative diseases, single cell fluorescence imaging

• Investigating the effects of neuroprotective and/or neurodegenerative agents on differentiated SH-SY5Y cells

• Investigating the antiinflammatory effects of an endemic plant (Sideritis brevibracteata) and Vitamins E and C on differentiated SH-SY5Y cells

• Investigating the effects of cardiac drugs on differentiated SH-SY5Y cells

• Collecting gait, blood and MRI data from stroke patients and investigating correlations between different modalities

• Whole-cell Patch-clamp

• Electrophysiology

• Atomic Force Microscopy

• Mechanical Properties of the Cells

• Fluorescence Imaging

• Cell Culture

• Immunocytochemistry

• Stroke

• Wearable Gait Analysis

• MRI
  
  
  

  Techniques

  "In vitro" whole-cell patch clamp and intracellular imaging of ionic movements
  Calcium and fluorescence imaging

  Collaborations

  Doç. Dr. Otar Akanyeti

  Dr. Federico Villagra (Aberystwyth University- Galler)