Emine Sümeyra Turalı Emre

Rank & Status: 

Assistant Professor

Biography: 

Dr. Emine Sümeyra Turalı-Emre joined Boğaziçi University in 2024,, where she combines her expertise in nanotechnology, biomedical engineering, and data science to solve critical healthcare challenges. Her research focuses on engineering inorganic nanoparticles for applications such as drug and gene delivery, antibacterial and anticancer treatments, bone regeneration, and extracellular vesicle capturing for diagnostics.

Dr. Turalı-Emre began her academic journey with a BSc in Molecular Biology and Genetics from Istanbul University. She then joined Harvard Medical School and MIT as a Research Associate under Dr. Utkan Demirci’s supervision, contributing to groundbreaking work in tissue engineering, cancer model development, and stem cell niche design. She earned her MSc and PhD in Biomedical Engineering from the University of Michigan, where she conducted innovative research under Dr. Nicholas A. Kotov. Her PhD thesis, Engineering Biomimetic Nanoparticles for Biomedical Applications, explored the design of nanoparticles for DNA and drug delivery, providing foundational insights into their therapeutic potential.Dr. Turalı-Emre continued her research as a Postdoctoral Fellow in Chemical Engineering at the University of Michigan, where she engineered chiral inorganic nanoparticles for advanced diagnostics and therapeutics. In collaboration with Dr. Scott VanEpps from the University of Michigan Medical School, she developed nanoparticle systems to combat biofilms and antibiotic-resistant bacteria, including MRSA. Her postdoctoral research also included computational modeling of nanoparticle-protein interactions and multi-scale chiral properties. After joining Boğaziçi University, she extended her collaboration with the University of Michigan as a Visiting Scholar, contributing to Coulter Translational Research Partnership projects focused on designing devices for extracellular vesicle capture, optimizing RNA isolation from biofilms, and developing antibacterial surfaces using chiral nanoparticles. Dr. Turalı-Emre’s work has been featured in leading journals such as Advanced Materials, Matter, and PNAS, with several publications highlighted on journal covers, including Advanced Materials. She is a member of Sigma Xi, The Scientific Research Honor Society, and has been recognized with several awards, including the BioInterfaces Research Community Innovator Award.

Passionate about cultivating interdisciplinary collaboration and DEI (diversity, equity, and inclusion), Dr. Turalı-Emre welcomes undergraduate, graduate, and non-traditional students from various fields, including engineering, life sciences, and computer science, to join her lab. Her lab provides a vibrant environment for conducting impactful research and contributing to transformative innovations in healthcare.

Education: 
  • Fast Forward Medical Innovation FastPace Program, University of Michigan, 2024

  • PhD, Biomedical Engineering, University of Michigan, 2021
    Thesis: Engineering Biomimetic Nanoparticles for Biomedical Applications

    • Translational Research Education Certificate
  • MSc, Biomedical Engineering, University of Michigan, 2015

  • BSc, Molecular Biology and Genetics, Istanbul University, 2008

Experience: 
  • Assistant Professor, Institute of Biomedical Engineering, Boğaziçi University, 2024–Present
    Leading research in nanotechnology for healthcare applications, including drug delivery, antibacterial treatments, and AI-powered nanoparticle design.

  • Visiting Scholar, University of Michigan, 2024
    Contributed to Coulter Translational Research Partnership projects, focusing on extracellular vesicle capture, optimizing RNA isolation from biofilms, and developing antibacterial surfaces using chiral nanoparticles.

  • Postdoctoral Research Fellow, Chemical Engineering, University of Michigan, 2021–2024
    Engineered chiral inorganic nanoparticles for advanced diagnostics and therapeutics. Collaborated with the University of Michigan Medical School on antibacterial nanoparticle research for biofilms and antibiotic-resistant bacteria.

  • Graduate Research Assistant, Biomedical Engineering, University of Michigan, 2015–2021
    Researched nanoparticle synthesis for drug and DNA delivery. Managed interdisciplinary collaborations and mentored undergraduate researchers.

  • MSc Researcher, Biomedical Engineering, University of Michigan, 2012–2015
    Investigated nanoparticle synthesis and its impact on size, shape, and charge for biomedical applications.

  • Research Associate, Harvard Medical School and MIT, 2008–2010
    Engineered bladder tissue, developed cancer models, and created stem cell niches.

Research Areas: 

Chiral nanoparticles, antibacterial nanoparticles, extracellular vesicle capturing, AI-driven nanoparticle-protein interactions, drug and gene delivery systems, cancer therapies, translational nanotechnology, and multidisciplinary approaches to address biomedical challenges

Awards: 
  • BioInterfaces Research Community Innovator Award, 2024
  • Full Member, Sigma Xi, The Scientific Research Honor Society, 2024
  • Women in Science and Engineering, Cinda Sue Davis STEM Equity Leadership Award (Nominee), 2024
  • Women in Science and Engineering, Willie Hobbs Moore Achievement Award (Nominee), 2024
  • Selected Participant, AI in Science & Engineering Summer Academy, 2023
  • Awardee, 1-Year Membership, American Association for the Advancement of Science (AAAS), 2021
  • Honorable Mention, Advanced Graduate Research Competition, UM Engineering Research Symposium, 2021
  • Nano Scribe Scholar, Micro-Nanotechnologies for Medicine Conference, 2019
  • Featured in U-M College of Engineering Magazine (6-page article), 2019
  • North Campus Deans’ Martin Luther King Spirit Award (Nominee), 2019
  • Full Scholarship, Turkish Ministry of Education (PhD and MSc studies), 2011–2019
  • Finalist, Society of Women Engineers Collegiate Research Competition (WE18), 2018
  • Best Research Poster, Biological Science, Michigan Microscopy & Microanalysis Society Annual Meeting, 2017
  • Grad-Student Spotlight, UM Graduate Society of Women Engineers, 2017
  • First Place Winner, Tissue and Cellular Biology Session, UM Engineering Graduate Symposium, 2016
Research Projects: 

Currently, Dr. Turalı-Emre leads a TÜBİTAK-BİLGEM project in collaboration with Dr. Betül Özateş from the Institute of Data Science and Artificial Intelligence. Together, they are developing an AI-driven database to optimize antibacterial nanoparticles for diagnostics and treatments, bridging nanotechnology and artificial intelligence.

Publications: 

Selected Publications

  • McGlothin, C. N., Whisnant, K. G., Turalı-Emre, E. S., & Kotov, N. A. Coupled self-replication and self-assembly of inorganic nanoparticles into biosimilar networks. Matter (2024, in press).

  • Kang, Y. T., Kim, J. Y., Turalı-Emre, E. S., Jang, H. J., Cha, M., Kumari, A., Palacios-Rolston, C., Subramanian, C., Purcell, E., Owen, S., Lim, C. M., Reddy, R., Jolly, S., Ramnath, N., Nagrath, S., & Kotov, N. A. Chiroptical detection and mutation analysis of cancer-associated extracellular vesicles in microfluidic devices. Matter 2024, 10.1016/j.matt.2024.09.005.

  • Yao, H., Fan, Y., Turalı-Emre, E. S., Li, N., Ge, M., Wang, J., & Wei, J. Enhancing antibacterial defense with alginate-modified ZnO nanoparticles against biofilm formation. Int. J. Biol. Macromol. 2024, 280, 1, 10.1016/j.ijbiomac.2024.135739.

  • Cha, M., Ma, J., Kim, J. Y., Turalı-Emre, E. S., & Kotov, N. A. Graph-theoretical chirality measure and chirality–property relations for chemical structures with multiscale mirror asymmetries. Chirality 36, e23678 (2024). 10.1002/chir.23678.

  • Kim, J. Y., McGlothin, C., Cha, M., Pfaffenberger, Z. J., Turalı-Emre, E. S., Choi, W., Kim, S., Biteen, J., & Kotov, N. A. Direct–write printing of plasmonic nanohelicoids by circularly polarized light. Proc. Natl. Acad. Sci. USA 121, e2312082121 (2024). 10.1073/pnas.2312082121.

  • Gao, R., Xu, X., Kumar, P., Liu, Y., Zhang, H., Guo, X., Sun, M., Colombari, F., De Moura, A., Hao, C., Cha, M., Turalı-Emre, E. S., Ma, J., Xu, L., Kuang, H., Kotov, N. A., & Xu, C. Efficient agglutination of various corona viruses by tapered chiral nanoparticles. Proc. Natl. Acad. Sci. USA 121, e2310469121 (2024). 10.1073/pnas.2310469121.

  • Turalı-Emre, E. S., Emre, A. E., Vecchio, D. A., Kadiyala, U., VanEpps, S. J., & Kotov, N. A. Self-assembly of iron sulfide nanoparticles into compartmentalized supraparticles as artificial viruses for gene and gene therapies. Adv. Mater. 35, 23 (2023). 10.1002/adma.202211244.

  • Cha, M., Turalı-Emre, E. S., Xiao, X., Kim, J. Y., Bogdan, P., VanEpps, S. J., Violi, A., & Kotov, N. A. Unifying structural descriptors for biological and bioinspired nanoscale complexes. Nat. Comput. Sci. 2, 243–252 (2022). 10.1038/s43588-022-00229-w.

  • Baranwal, M., Magner, A., Saldinger, J., Turalı-Emre, E. S., Elvati, P., Kozaker, S., VanEpps, S. J., Kotov, N. A., Violi, A., & Hero, A. O. Struct2Graph: A graph attention network for structure-based predictions of protein-protein interactions. BMC Bioinformatics 23, 370 (2022). 10.1186/s12859-022-04910-9.

  • Kadiyala, U., Turalı-Emre, E. S., Bahng, J. H., Kotov, N. A., & VanEpps, S. J. Unexpected insights into the antibacterial activity of zinc oxide nanoparticles against methicillin-resistant Staphylococcus aureus (MRSA). Nanoscale 2018, 10.1039/C7NR08499D.

Reviewer for: 

Frontiers in Molecular Biosciences                                                                       

E-Mail: 
eminesumeyra.turali@bogazici.edu.tr , esumeyra@umich.edu