Cellular Imaging & Electrophysiology Laboratory

Cellular Imaging and Electrophysiology Laboratory

Prof. Dr. Hale Saybasili
 

Research Fields:

  • Electrophysiological recordings from brain slice cells and imaging of intracellular ionic movements are accomplished. Also mechanisms of pathological and pharmocological approaches are studied.
  • Electrical activity measurements and potential for modelling neurodegenerative diseases, single cell fluorescence imaging
  • Investigating the effects of neuroprotective and/or neurodegenerative agents on differentiated SH-SY5Y cells
  • Investigating the antiinflammatory effects of an endemic plant (Sideritis brevibracteata) and Vitamins E and C on differentiated SH-SY5Y cells
  • Investigating the effects of cardiac drugs on differentiated SH-SY5Y cells
  • Collecting gait, blood and MRI data from stroke patients and investigating correlations between different modalities
  • Whole-cell Patch-clamp
  • Electrophysiology
  • Atomic Force Microscopy
  • Mechanical Properties of the Cells
  • Fluorescence Imaging
  • Cell Culture
  • Immunocytochemistry
  • Stroke
  • Wearable Gait Analysis
  • MRI

                                                   

                                                                                                     

                                                                                                                          

Techniques                                                                                                                          

"in vitro" whole-cell patch clamp and intracellular imaging of ionic movements 
Calcium and fluoresence imaging

Collaborations

Doç. Dr. Otar Akanyeti

Dr. Federico Villagra (Aberystwyth university- Galler)